Streptococcal infections among children in a residential home: III. Some factors influencing susceptibility to infection

Author:

Holmes Margaret C.,Williams R. E. O.,Bloom C. V.,Hirch Ann,Lermit ,Woods Eileen

Abstract

Children in a residential home whose tonsils had been removed had lower attack rates for streptococcal sore throat than tonsillectomized children. Tonsillectomy did not have a consistent effect on respiratory tract illness.Tonsillectomy has a similar effect on the outcome of individual exposures to streptococcal infection; the difference was more marked for illness than for simple colonization.The apparent benefit from tonsillectomy could not be attributed to the ageing of the child, and was considered real. Its magnitude did not seem, however, great enough to justify a policy of extensive tonsillectomy, particularly in view of the possible risks to the child.A child who had been ill with infection due to one streptococcal type rarely became ill when re-exposed to the same type. In addition there was some evidence in children with tonsils of an immunity, perhaps short lived, which was clearly not type-specific.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference12 articles.

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2. Poliomyelitis and Tonsilectomy. Medical Research Council Committee on inoculation procedures and neurological lesions;Lancet,1955

3. Protection between strains of heterologous agglutinogenic types of β-hemolytic streptococci of Group A. III. Further observations;Evans;J. Immunol.,1946

4. Streptococcal infections among children in a residential home: I. Introduction and definitions: the incidence of infection

5. Streptococcal infections among children in a residential home: IV. Outbreaks of infection

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