Abstract
Cytokines were first recognized as factors involved in the immune responses. However, emerging evidence suggests that cytokines serve as the unanimous language through which cells in organ systems as diverse as hypothalamus to endometrium communicate. Evidence for the participation of these factors in the normal function of the endometrium and uteroplacental unit and development of the embryo is being recognized. This review will highlight the significant insight gained over the past several years for the role of cytokines in the field of reproductive biology. Major emphasis will be placed on interleukins, tumour necrosis factor-α, transforming growth factors, colony stimulating factors and interferon-gamma.
Publisher
Cambridge University Press (CUP)
Subject
Obstetrics and Gynaecology
Cited by
9 articles.
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