Metabolic adaptation during pregnancy in winter-shorn sheep

Abstract

SummaryThe effects of winter shearing on ewe live weight, body condition score (BCS) and the concentrations of glucose, non-esterified fatty acids (NEFA), 3-hydroxybutyrate, growth hormone (GH), cortisol, insulin and the thyroid hormones in plasma plus that of oxygen and carbon dioxide in jugular vein blood and packed cell volume (PCV) were measured at weekly intervals over the final 7 weeks of pregnancy in two groups of multiple-bearing shorn and unshorn pregnant ewes.Shorn ewes lost 47% more live weight than unshorn controls over the period from the day of being shorn to immediately after lambing. There was a significant decrease in BCS in both groups between 45 and 9 days before lambing. Three days after shearing the plasma NEFA concentration was higher in the shorn group but there were no other significant differences between shorn and unshorn groups in the plasma concentrations of NEFA, cortisol or insulin over the remaining 7 weeks of pregnancy. Both the PCV and concentration of carbon dioxide in blood were higher in shorn sheep throughout the final 6 weeks of pregnancy indicating they were making metabolic adaptations to long-term cold exposure. This response may have been mediated via an increase in thyroid hormone concentrations which were higher throughout the 7-week sampling period in shorn animals compared with unshorn controls. A decrease in ambient temperature was associated with a significant increase in the plasma concentration of GH and glucose in shorn animals. At 2 weeks before lambing there was a decrease in the plasma glucose concentration and an increase in 3-hydroxybutyrate concentration in the unshorn ewes, but these changes were not observed in the shorn animals. It is concluded that winter shearing of the pregnant ewe results in an increased loss of maternal body tissues and metabolic adaptations to long-term cold exposure without any of the changes associated with an increase in energy expenditure during the final third of pregnancy.