The effect of treatment by prostaglandin analogue (ICI–80, 996) or progestagen (SC-9880) on ovulation and fertilization in cyclic ewes

Abstract

SummaryMature cyclic ewes were treated intravaginally with sponges impregnated with 30 mg SC-9880 (G. D. Searle) or intramuscularly with 100 μg Cloprostenol (I.C.I. 80, 996) and examined subsequently for oestrus, ovulation and fertilization. At 70 h after the end of treatment, 90% of ewes treated with SC-9880 and 45% of those treated with Cloprostenol had ovulated. Of ewes yielding eggs at 100 h a significantly higher proportion of SC-9880 treated sheep showed evidence of fertilization (69% v. 7%).