Author:
Greenblatt David J.,Shader Richard I.
Abstract
SUMMARY:Benzodiazepine derivatives are neuropharmacologically similar but may appear clinically distinct due to pharmacokinetic differences. The clinical effects of single doses depend mainly on rates of drug absorption and distribution, whereas drug accumulation is a major determinant of clinical action during
multiple dosage. This paper outlines potential clinical implications of benzodiazepine pharmacokinetics.
Publisher
Cambridge University Press (CUP)
Subject
Clinical Neurology,Neurology,General Medicine
Cited by
2 articles.
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1. New Drugs for Pediatric Epilepsy;Seminars in Pediatric Neurology;2010-12
2. Benzodiazepines: Towards More Logical Use;Scottish Medical Journal;1982-10