Author:
Huxtable R.,Azari J.,Reisine T.,Johnson P.,Yamamura H.,Barbeau A.
Abstract
SummaryThe distribution of amino acids in two Friedreich's ataxia brains is compared to 4 control brains. Glutamate and G A BA were decreased in the ce r ebe l-lar hemispheres and/or in the vermis. Taurine concentrations were uniformly elevated throughout the areas studied. Taurine /glutamate and taurine/ GABA ratios were consistently elevated in Friedreich's ataxia brains, whereas glutamate/ glutaminę ratios were consistently decreased (with normal glutaminę concentrations).
Publisher
Cambridge University Press (CUP)
Subject
Clinical Neurology,Neurology,General Medicine
Cited by
32 articles.
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