ビタミンKの生体内変換を担う酵素と変換の意義
Author:
Affiliation:
1. Faculty of Pharmaceutical Sciences, Kobe Gakuin University
Publisher
Japanese Society of Nutrition and Food Science
Subject
General Materials Science
Link
https://www.jstage.jst.go.jp/article/jsnfs/76/4/76_199/_pdf
Reference29 articles.
1. 1) Thijssen HH, Vervoort LM, Schurgers LJ, Shearer MJ (2006) Menadione is a metabolite of oral vitamin K. Br J Nutr 95: 260-6.
2. 2) Shearer MJ (2000) Role of vitamin K and gla proteins in the pathophysiology of osteoporosis and vascular calcification. Curr Opin Clin Nutr Metab Care 3: 433-8.
3. 3) Tabb MM, Sun A, Zhou C, Grün F, Errandi J, Romero K, Pham H, Inoue S, Mallick S, Lin M, Forman BM, Blumberg B (2003) Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem 278: 43919-27.
4. 4) Ichikawa T, Horie-Inoue K, Ikeda K, Blumberg B, Inoue S (2006) Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem 281: 16927-34.
5. 5) Ichikawa T, Horie-Inoue K, Ikeda K, Blumberg B, Inoue S (2007) Vitamin K2 induces phosphorylation of protein kinase A and expression of novel target genes in osteoblastic cells. J Mol Endocrino 39: 239-47.
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