Role of Labetalol in Control of Hypertension during Pregnancy

Abstract

Aim: To valuate the effectiveness of labetalol in controlling hypertension during pregnancy. Study design: Descriptive case series Place and duration of study: Department of Obstetrics & Gynaecology, Allama Iqbal Medical College/Jinnah Hospital Lahore from 1st September 2018 to 31st March 2019. Methodology: Sixty four patients were enrolled. All the patients were started with lowest effective dose of100mg orally three times daily and if required after 72 hours, the escalation dose up to 200mg every 8hours. When adequate reduction in blood pressure was obtained it was labelled as achievement of primary end point. Results: The age range between 18-35 years with mean age 25.8±5.0 years. There were 12 primigravida (18.8%) and multigravida 52(81.2%). Reduction in blood pressure was observed in56 cases (87.5%). Conclusion: The labetalol appears to be an effective agent in controlling hypertension during pregnancy with possible advantages and no apparent disadvantage during its use. Keywords: Pregnancy-induced hypertension; Labetalol, Control of hypertension