The Efficacy of CT Scan in Evaluation of Hepatic Tumors taking Histopathology as Gold Standard

Abstract

Background and Aim: The prevalence of hepatic tumors is most common among developing countries of Asia compared to Europe and Western countries. In Pakistan, hepatic tumors are the 4thcommon disorder. The current study aims to evaluate the efficacy of hepatic tumors taking histopathology as a gold standard. Materials and Methods: This cross-sectional study wascarried out on 120 patients who underwent CT scans for hepatic tumors inradiology department of Sughra Shafi Medical Complex / Sahara Medical College, Narowal and Children Hospital &Institute of Child Health,Multan during the period of six months from 1st September 2020 to 2nd March 2021. The age range for all the patients was 29 to 80 years with mean ±SD(52±5.32) followed by hepatic tumors diagnosed based on histopathology as agold standard and assessed with CT. The prevalence of colorectal carcinoma was 22(18.33%), while other common parameters were pancreas, stomach adenocarcinoma, and biliarytree 13 (10.83%), and hepatocellular carcinoma 85 (70.84%). Unresectable tumors inpatients were assessed with percutaneous biopsy of the hepatic lesion and correlatedwith CT results. Resectability predictionwas assessed with CT findings accuracy in all the patients who had tumors onthe basis of CT images and had surgery. Results: All the patients of hepatic tumors were assessed with CT scans and histopathology was taken from each participant. Accuracy, sensitivity and specificity of CT scans was 67.33%, 62.35% and 73.85% respectively. The positive and negative predictive values were about 75.71% and 60% respectively. Statistical significance was (P<0.05) set as a standard.SPSS version 20 was used for data analysis. Conclusion:Our study found that hepatic tumors can be assessed byarterial portography with resectability by CT scans. In our study, out of 120 patientshad spared surgery and only 17% of patients were considered as resectable duringarterial portography on CT scans findings. CT scanplays a pivotal role in assessing hepatic tumors. Accuracy, sensitivity and specificity of CT scans was 67.33%, 62.35% and 73.85% respectively. The positive and negative predictive values were about 75.71% and 60% respectively. Keywords:Hepatic Tumors, CT scans,Histopathology