Post-Acute Covid-19 Syndrome

Abstract

The coronaviruses (CoVs) belongs to the subgroup Orthocoronavirinae in the family Coronaviridae, Order Nidovirales.1 During 2002, the China reports first outbreak of SARS quickly spread worldwide, leads to approximately 11% fatality rate while during 2012;2 Middle East Respiratory Syndrome (MERS) originates in Saudi Arabia followed by its spread worldwide with 37% mortality.3 During December 2019, an pneumonia of unknown etiology has been detected in vast majority of patients resides in Wuhan City, Central China and Hubei Province.4 The Genomic research has been identified that this pneumonia considered as coronavirus disease 2019 caused by novel corona virus (CoV) labeled as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), formerly called as 2019-novel coronavirus (2019-nCoV).5 The screening and management strategies are not sufficient to end the battled against COVID-19.6 The survivors face various long terms symptoms produced by COVID-19 which are still the matter of debate.7 The literature reported 50-90% individuals have persistent symptoms and considered as long-haulers but due to confounders as gender, age, race, duration and severity of infection, short term study period and follow ups the results are hampered and limited.8