To Study the Frequency of Albuminuria in Diabetics Brought in with Stroke: A survey at Tertiary Care Hospital

Abstract

Background: Albuminuria is thought to be a separate risk factor for stroke. A strong association between diabetes related albuminuria and stroke has been published in the international literature. Albuminuria being a sign of endothelial dysfunction, atherosclerosis is a strong predictor of strokes. Aim: To investigate the albuminuria as a predictor of stroke in diabetics in our population. Study design: Observational study. Place and duration of study: This study was done in the Department of Neurology, Sharif Medical & Dental College/Hospital, Lahore from January to August 2019. Methodology: One hundred and fifty diabetic patients having ages 25 to 75 years presented with stroke were enrolled in this study. Demographics (age, sex, residence and socio-economic status) of the included population and types of stroke were recorded on study proforma after getting brain CT of each patient. Urine for albuminuria was examined under microscope. Results: In this study (63%) were males and 37% were females with M:F ratio 2.54:1. Major portion of the patients (43%) were ages between 25-45 years mean±SD 51.62±8.45. Ischemic stroke was found in 114 (76%) hemorrhagic in 24(16%) and undetermined in 12(8%) patients respectively. Albuminuria was found in 72(48%) patients, Group A 40(69%) had ischemic stroke, 10(17%) had hemorrhagic and 8(14%) had undetermined stroke. Conclusion: It is concluded that is strong relation between microvascular complications with macrovascular complication of diabetes (i.e. albuminuria with stroke). The stoke patients with diabetes has more frequency of albuminuria as compared to non diabetics. Keywords: Albuminuria, T2DM, Stroke, Hemorrhagic.