Association of AVPR1A Polymorphism with Criminal Intent

Abstract

Background: The human behavior is influenced by genetic as well as environment components. Likewise, the aggressive behavior having an intent of criminality is also governed by both environmental and genetic makeup. Aim: The genetic element has been explored by analyzing the microsatellite RS1 and RS3 of AVPRIA gene which showed strong variations in short tandem repeats (STRs) of convicted offenders when they were compared with normal population. Methods: Blood samples of 100 convicted offenders were taken and DNA was extracted using PCI protocol. The PCR was then carried out using primers and the products were send for gene sequencing. The results were compared with that of general population having no history of crime or psychological abnormality. Results: The microsatellite RS1 and RS3 of AVPRIA gene showed strong variations in short tandem repeats (STRs) of convicted offenders when they were compared with normal population. Keywords: AVPR1A, criminal intent, PCR