Frequency of Iron Deficiency Anemia among End-Stage Renal Disease Patients on Thrice Weekly Maintenance Hemodialysis

Abstract

Background: Anemia secondary to chronic kidney disease (CKD) is a major contributor to high morbidity and mortality among CKD patients. These patients develop iron deficiency anemia (IDA) either due to functional or absolute iron defects. KDIGO 2012 guidelines and 2013 European Renal Best Practice guidelines recommend iron replacement to achieve TSAT of 25-30% and the serum ferritin of 500 ng/ml. Aim: To determine the frequency of Iron-deficiency Anemia in end-stage renal disease patients on thrice-weekly maintenance hemodialysis. Study design: Cross-Sectional Study Place and duration of study: Dialysis Unit of Sir Ganga Ram Hospital, Lahore from 10th April 2019, to 10th October 2019. Methodology: One hundred and six cases were enrolled. Blood samples were taken and investigations to document anemia like hemoglobin levels, serum iron, serum TIBC, serum ferritin, and transferrin saturation were measured and IDA was recorded. Results: Seventy one (67.0%) were males and 35 (33.0%) were females. The mean age was 47.4±12.5 years. Iron deficiency anemia was found in 38 (35.8%) patients. Conclusion: Iron deficiency anemia is common among individuals with end-stage renal disease patients on thrice-weekly maintenance hemodialysis. Key words: End-stage renal disease (ESRD), Haemodialysis, Iron deficiency anemia (IDA)