Buccal midazolam for treatment of pediatric status epilepticus in community settings in Japan: A phase 3 open-label extension study
Author:
Affiliation:
1. National Hospital Organization Minami-Okayama Medical Center
2. Takeda Pharmaceuticals Inc.
3. Takeda Pharmaceutical Company Limited, Japan Development Center
Publisher
The Japan Epilepsy Society
Subject
Neurology (clinical)
Link
https://www.jstage.jst.go.jp/article/eands/15/1/15_1/_pdf
Reference12 articles.
1. [1] Trinka E, Hofler J, Leitinger M, Brigo F. Pharmacotherapy for Status Epilepticus. Drugs 2015; 75: 1499–1521.
2. [2] McIntyre J, Robertson S, Norris E, Appleton R, Whitehouse WP, Phillips B, Martland T, Berry K, Collier J, Smith S, Choonara I. Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: a randomised controlled trial. Lancet 2005; 366: 205–210.
3. [3] Nishiyama I, Ohtsuka Y, Tsuda T, Kobayashi K, Inoue H, Narahara K, Shiraga H, Kimura T, Ogawa M, Terasaki T, Ono H, Takata T. An epidemiological study of children with status epilepticus in Okayama, Japan: Incidence, etiologies, and outcomes. Epilepsy Research 2011; 96: 89–95.
4. [4] Anderson M. Buccal midazolam for pediatric convulsive seizures: efficacy, safety, and patient acceptability. Patient Prefer Adherence 2013; 7: 27–34.
5. [5] Yoshinaga H, Benitez A, Takeda S, Fournier M, Kugler AR. A phase 3 open-label study of the efficacy, safety and pharma-cokinetics of buccally administered midazolam hydrochloride for the treatment of status epilepticus in pediatric Japanese subjects. Epilepsy Research 2021; 174: 106651.
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