Jab1 Silencing Inhibits Proliferation and Sensitizes to Cisplatin in Biliary Tract Cancer
Author:
Funder
Ministry of Health and Welfare
Publisher
Korean Cancer Association
Subject
Cancer Research,Oncology
Link
http://e-crt.org/upload/pdf/crt-2018-375.pdf
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1. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
2. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
3. The Cytoplasmic Shuttling and Subsequent Degradation of p27Kip1 Mediated by Jab1/CSN5 and the COP9 Signalosome Complex
4. Jab1 Induces the Cytoplasmic Localization and Degradation of p53 in Coordination with Hdm2
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