Affiliation:
1. izmir atatürk eğitim ve araştırma hastanesi
2. İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ, TIP FAKÜLTESİ
Abstract
Objectives: This study aims to investigate the potential differential impact of COVID-19 infection on pregnant women compared to non-pregnant individuals of childbearing age by evaluating laboratory findings from both inpatient and outpatient cases.
Material and Methods: From the onset of COVID-19 in Turkey in March 2020 until the commencement of vaccination, a total of 94 COVID-19 patients were included in three separate groups: pregnant women and non-pregnant individuals with COVID-19 (with and without pneumonia). Sociodemographic data and examination findings were retrospectively retrieved from the hospital information system.
Results: The study revealed that pregnant women, with a mean age of 28.87±1.38, experienced a significantly shorter mean length of hospital stay of 5.03±0.49 days compared to the other groups (p<0.001). Notably, pregnant women exhibited significant variations in urea, creatinine, white blood cell count, neutrophil count, hemoglobin, and hematocrit values in comparison to the other groups (p<0.001). Moreover, there were significant differences among the three groups concerning neutrophil and lymphocyte percentage values (p<0.001).
Conclusion: The study suggests that COVID-19 infection in pregnant women is associated with more favorable clinical outcomes, shorter length of hospital stay, and relatively moderate alterations in laboratory findings when accounting for pregnancy-induced changes. It is implied that pregnancy might not pose as substantial a risk factor for severe COVID-19 infection as advanced age or underlying chronic conditions such as diabetes, asthma, COPD, and malignancy.
Publisher
Balikesir Medical Journal
Subject
Geriatrics and Gerontology
Reference30 articles.
1. Madjunkov M, Dviri M and Librach C. A comprehensive review of the impact of COVID-19 on human reproductive biology, assisted reproduction care and pregnancy: a Canadian perspective. J Ovarian Res 2020;13(1):140. https://doi.org/10.1186/s13048-020-00737-1
2. Lu Q and Shi Y. Coronavirus disease (COVID-19) and neonate: What neonatologist need to know. J Med Virol 2020;92:564-567. https://doi.org/10.1002/jmv.25740
3. World Health Organization Q&A on coronaviruses (COVID-19)- April 12, 2020. https://www.who.int/emergencies/diseases/novelcoronavirus-2019/question-and-answe rs-hub/q-a-detai l/qa-coronaviruses. Accessed on July 2020. In: WHO, editor.
4. Liu M, Wang T, Zhou Y, Zhao Y, Zhang Y, Li J. Potential Role of ACE2 in Coronavirus Disease 2019 (COVID-19) Prevention and Management. J Transl Int Med 2020;8(1):9-19. https://doi.org/10.2478/jtim-2020-0003
5. Weiss SR, Navas-Martin S. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol Mol Biol Rev 2005;69(4):635-664. https://doi.org/10.1128/mmbr.69.4.635-664.2005