Affiliation:
1. Westminster Free Clinic and Community Care Center, Thousands Oak, CA
Abstract
Polypharmacy, which refers to using multiple medications by an individual, is
becoming increasingly common in the aging population. Although it can be beneficial
in treating complex medical conditions, it also carries inherent risks, such as adverse
drug reactions, drug interactions, cognitive impairment, and increased healthcare
costs. With increased medication use, it is essential to consider the risks and benefits
of each prescribed medication. Evidence-based guidelines, such as the Beers Criteria
and the Screening Tool of Older Persons’ Prescriptions criteria, can help healthcare
providers reduce the risks of polypharmacy. Deprescribing, the process of reducing
or stopping medication use that is no longer necessary or potentially harmful, is
becoming increasingly important in managing polypharmacy. The 5Rs Framework and
the Medication Appropriateness Index are two examples of clinical practice guidelines
for deprescribing. Communication and collaboration between healthcare providers and
patients, gradual tapering of medication, and involvement of patients and caregivers
in decision-making are important considerations for deprescribing in primary care.
This article provides an overview of the prevalence and negative consequences of
polypharmacy, evidence-based guidelines for reducing polypharmacy, clinical practice
guidelines for deprescribing, and considerations for deprescribing in primary care.
Publisher
The Medical Journal of Southern California Clinicians