<i>C. difficile</i>-infection and microbyota in newborns: resolved and outstanding issues-Reference-Cited by-同舟云学术

C. difficile-infection and microbyota in newborns: resolved and outstanding issues

Published:2021-10-06 Issue:3 Volume:20 Page:39-47
ISSN:2072-8107
Container-title:CHILDREN INFECTIONS
language:
Short-container-title:Det. infekc.

Author:

Mazankova L. N.¹^ORCID,Perlovskaya S. G.²^ORCID,Rubalchenko O. V.³^ORCID

Affiliation:

1. Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation

2. Children's City Hospital No 9

3. Educational and Research Medical Center in the Administrative Department of the President of the Russian Federation

Abstract

The article presents an analytical review of the works of domestic and foreign authors on the problem of studying the peculiarities of the formation of the intestinal microbiota and risk factors for the development of microdysbiosis in newborns with the activation of opportunistic bacteria, including C. difficile. Special attention is paid to the effect of antibiotics on the state of the intestinal microbiota and the activation of toxigenic strains of C. difficile. Divergent views on the role of toxigenic strains of C. difficile in the development of infectious pathology of newborns are presented.

Publisher

Journal of Childrens Infections

Subject

General Medicine

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