Affiliation:
1. Moscow Multidisciplinary Clinical Center «Kommunarka» of the Moscow Department of Health
2. Federal Scientific Center for Research and Development of Immunobiological Preparations named after. M.P. Chumakov RAS (Polio Institute); Russian National Research Medical University named after N.I. Pirogov Ministry of Health of Russia
3. Russian National Research Medical University named after N.I. Pirogov Ministry of Health of Russia
4. Federal Scientific Center for Research and Development of Immunobiological Preparations named after. M.P. Chumakov RAS (Polio Institute)
5. State budgetary healthcare institution «Infectious Clinical Hospital No. 1» of the Moscow Department of Health
6. Moscow Multidisciplinary Clinical Center «Kommunarka» of the Moscow Department of Health; Russian National Research Medical University named after N.I. Pirogov Ministry of Health of Russia
Abstract
Purpose of the work: to conduct a clinical-epidemiological analysis of intestinal infections in a pediatric infectious diseases hospital and the effectiveness of the PEWS scale.Materials and methods: a retrospective study was conducted at the Moscow City Clinical Hospital «Communarka» and City Clinical Hospital No. 1 in the pediatric infectious disease departments from June 1, 2023, to August 31, 2023. Laboratory, clinical, and anamnestic data were obtained from the medical information system «EMIAS» and the laboratory information system (LIS) «ALISA». The study analyzed 838 medical records of children with acute respiratory infections.Results: when conducting a statistical analysis of indicators in two groups (group 1 — PEWS ≥ 3 points, recorded at least once during the entire period of hospitalization, group 2 — PEWS from 1 to 2 points, recorded at least once during hospitalization period) no significant differences were observed in terms of etiology, age, day of illness, blood test results, and length of hospital stay. All patients had a moderate form of acute respiratory infection, however, patients with PEWS ≥ 3 points required increased attention from medical staff and had a higher risk of deterioration without additional medical intervention, with the most significant risk in predicting deterioration being related to changes in the cardiovascular system. All children were discharged home in satisfactory condition with PEWS = 0.Conclusion: In our conducted research, for the first time in the Russian Federation, the experience of using the PEWS scale in pediatric practice for patients with gastrointestinal infections was applied with the aim of early detection of the risk of clinical deterioration. It can be assumed that the most significant risk in predicting deterioration in the condition of a child with acute gastrointestinal infection, as well as with acute respiratory infection, is predominantly due to disturbances in the cardiovascular system.
Publisher
Journal of Childrens Infections
Reference20 articles.
1. GBD Diarrhoeal Disease Collaborators. Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Infect Dis. 2017; 17:909—948
2. World Health Organization. Diarrhoeal disease. 2017. Available at: https://www.who.int/news-room/fact-sheets/detail/diarrhoeal-disease (Accessed April 25, 2019)
3. State report «On the state of sanitary and epidemiological well-being of the population of the Russian Federation in 2022» M.: Federal Service for Supervision of Consumer Rights Protection and Human Welfare, 2023:368. (In Russ.)
4. Clinical recommendations «Rotavirus gastroenteritis in children» approved in 2023. International public organization «Euro-Asian Society for Infectious Diseases» Interregional public organization «Association of Infectious Disease Doctors of St. Petersburg and Leningrad Region» (In Russ.)
5. Crawford SE, Ramani S, Tate JE, Parashar UD, Svensson L, Hagbom M, Franco MA, Greenberg HB, O'Ryan M, Kang G, Desselberger U, Estes MK. Rotavirus infection. Nat Rev Dis Primers. 2017 Nov 9; 3:17083. doi: 10.1038/nrdp.2017.83.