Safety and pharmacokinetics of single, dual, and triple antiretroviral drug formulations delivered by pod-intravaginal rings designed for HIV-1 prevention: A Phase I trial

Author:

Vincent Kathleen L.ORCID,Moss John A.ORCID,Marzinke Mark A.ORCID,Hendrix Craig W.ORCID,Anton Peter A.ORCID,Pyles Richard B.ORCID,Guthrie Kate M.ORCID,Dawson Lauren,Olive Trevelyn J.,Butkyavichene Irina,Churchman Scott A.,Cortez John M.,Fanter Rob,Gunawardana Manjula,Miller Christine S.,Yang Flora,Rosen Rochelle K.,Vargas Sara E.ORCID,Baum Marc M.ORCID

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Institute of Allergy and Infectious Diseases

National Center for Advancing Translational Sciences

Johns Hopkins Center for AIDS Research

Publisher

Public Library of Science (PLoS)

Subject

General Medicine

Reference58 articles.

1. Birx DL. Delivering an AIDS-free generation [Presentation]: The Henry J. Kaiser Family Foundation; 2014.

2. Fast-Track: Ending the AIDS Epidemic by 2030. Geneva, Switzerland: UNAIDS, 2014.

3. Prevention Gap Report. Geneva, Switzerland: UNAIDS, 2016.

4. Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women;Q Abdool Karim;Science,2010

5. Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men;RM Grant;N Engl J Med,2010

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