Time-Dependent Structural Alteration of Rituximab Analyzed by LC/TOF-MS after a Systemic Administration to Rats

Author:

Otani Yuki,Yonezawa AtushiORCID,Tsuda Masahiro,Imai Satoshi,Ikemi Yasuaki,Nakagawa Shunsaku,Omura Tomohiro,Nakagawa Takayuki,Yano Ikuko,Matsubara Kazuo

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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2. Lessons for the clinic from rituximab pharmacokinetics and pharmacodynamics;J Golay;MAbs,2013

3. Simultaneous analysis of multiple monoclonal antibody biotherapeutics by LC-MS/MS method in rat plasma following cassette-dosing;H Li;Aaps j,2013

4. Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry;M Qu;Mass Spectrom Rev,2016

5. Antibody structure, instability, and formulation;W Wang;J Pharm Sci,2007

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