A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate

Author:

O’Farrell Alice C.ORCID,Evans Rhys,Silvola Johanna M. U.,Miller Ian S.,Conroy Emer,Hector Suzanne,Cary Maurice,Murray David W.,Jarzabek Monika A.,Maratha Ashwini,Alamanou Marina,Udupi Girish Mallya,Shiels Liam,Pallaud Celine,Saraste Antti,Liljenbäck Heidi,Jauhiainen Matti,Oikonen Vesa,Ducret Axel,Cutler Paul,McAuliffe Fionnuala M.,Rousseau Jacques A.,Lecomte Roger,Gascon Suzanne,Arany Zoltan,Ky Bonnie,Force Thomas,Knuuti Juhani,Gallagher William M.,Roivainen Anne,Byrne Annette T.

Funder

AngioTox; a European Commission FP7 Industry Academia Pathways and Partnerships Marie Curie Award

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference47 articles.

1. FDA. Sutent Medication Guide (http://www.fda.gov/downloads/drugs/drugsafety/ucm219111.pdf) [PDF]. www.FDA.gov: Pfizer; 2013 [updated August 2013; cited 2014 13th May]. http://www.fda.gov/downloads/drugs/drugsafety/ucm219111.pdf.

2. Clinicaltrials.gov. List results, search of sunitinib http://www.clinicaltrials.gov/ct2/results?termsunitinib 2014 [cited 20/10/2014]. http://www.clinicaltrials.gov/ct2/results?term=sunitinib&recr=Open.

3. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship;DB Mendel;Clin Cancer Res,2003

4. Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib;BB Hasinoff;Mol Pharmacol,2008

5. Sunitinib adverse events in metastatic renal cell carcinoma: a meta-analysis;EM Ibrahim;Int J Clin Oncol,2013

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