Abstract
Aims
To characterizes Emiratis patients with Type 1 diabetes (T1D) and compares outcomes between continuous subcutaneous insulin infusion (CSII) versus multiple daily insulin injections (MDI) users. The WHO-Five Well-Being Index (WHO-5) score was used to screen for depression.
Methods
In this cross-sectional study; sociodemographic, clinical characteristics and insulin replacement regimens were collected on patients with T1D between 2015–2018.
Results
134 patients with mean age of 20.9±7.5 years were included. Females constitute 56.7% and 50.7% had diabetes duration of >10 years. Diabetic ketoacidosis (DKA) at presentation was reported in 46.3%. Average glycemic control over preceding 12months was satisfactory (less than 7.5%), suboptimal (7.5–9%), and poor (more than 9%) in 26.6%, 42.7% & 30.6% of the patients, respectively. Higher proportion of patients using CSII achieved satisfactory or suboptimal glycemic control compared to patients with MDI (P = 0.003). The latest median /IQR HbA1c was significantly lower (P = 0.041) in patients using CSII (8.2 /1.93%) compared to MDI (8.5/2.45%). There was no significant difference between two groups in DKA, severe hypoglycemia or total WHO-5 score.
Conclusions
CSII usage was associated with better glycemic control than MDI, although no difference in DKA and severe hypoglycemia. The overall glycemic control among Emiratis subjects with T1D is unsatisfactory and needs more rigorous patient counseling and education.
Funder
united arab emirates university
Publisher
Public Library of Science (PLoS)
Reference40 articles.
1. Huang Y. IDF Diabetes Atlas 8th Edition 2017.
2. Genetic Epidemiology of Type 1 Diabetes in the 22 Arab Countries;H. Zayed;Current diabetes reports,2016
3. Ketoacidosis at first presentation of type 1 diabetes mellitus among children: a study from;AA Shaltout;Kuwait. Sci Rep,2016
4. The accelerating epidemic of childhood diabetes;D. Dabelea;Lancet,2009
5. Prevalence of autoantibodies in type 1 diabetes patients and its association with the clinical presentation—UAE Eastern Region experience;N Al-Hassani;J Pediatr Endocrinol Metab,2014
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献