Combining Structural Modeling with Ensemble Machine Learning to Accurately Predict Protein Fold Stability and Binding Affinity Effects upon Mutation
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference76 articles.
1. Understanding the contribution of synonymous mutations to human disease;ZE Sauna;Nat Rev Genet,2011
2. A Good SNP May Be Hard to Find;M Hagmann;Science,1999
3. Searching for genetic determinants in the new millennium;NJ Risch;Nature,2000
4. Evolution and functional impact of rare coding variation from deep sequencing of human exomes;JA Tennessen;Science,2012
5. Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays;R Drmanac;Science,2010
Cited by 74 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. In silico energetic and molecular dynamic simulations studies demonstrate potential effect of the point mutations with implications for protein engineering in BDNF;International Journal of Biological Macromolecules;2024-06
2. Decoding molecular mechanisms for loss of function variants in the human proteome;2024-05-22
3. Developing similarity matrices for antibody-protein binding interactions;PLOS ONE;2023-10-26
4. Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels;PLOS Computational Biology;2023-09-15
5. Resolving Structure of ssDNA in Solution by Fusing Molecular Simulations and Scattering Experiments with Machine Learning;Advanced Theory and Simulations;2023-09-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3