Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor-Reference-Cited by-同舟云学术

Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor

Published:2014-06-30 Issue:6 Volume:9 Page:e100880
ISSN:1932-6203
Container-title:PLoS ONE
language:en
Short-container-title:PLoS ONE

Author:

Dumble Melissa,Crouthamel Ming-Chih,Zhang Shu-Yun,Schaber Michael,Levy Dana,Robell Kimberly,Liu Qi,Figueroa David J.,Minthorn Elisabeth A.,Seefeld Mark A.,Rouse Meagan B.,Rabindran Sridhar K.,Heerding Dirk A.,Kumar Rakesh

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference38 articles.

1. PI3K pathway alterations in cancer: variations on a theme;TL Yuan;Oncogene,2008

2. Characterization of a 3-phosoinositude-dependant protein kinase which phosphorylates and activates protein kinase B alpha;DR Alessi;Curr Biol,1997

3. Role of phosphatidylinositol 3, 4, 5- triphosphate in regulating the activity and localization of 3-phosphoinositide-dependant protein kinase-1;RA Currie;Biochem J,1999

4. Akt regulated pathways in prostate cancer;PK Majumder;Oncogene,2005

5. mTOR/Rictor is the Ser 473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes;RC Hresko;J Biol Chem,2005

Cited by 118 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chemoenzymatic Synthesis of Fluorinated L-α-Amino Acids;ACS Sustainable Chemistry & Engineering;2024-08-27

2. Scalable and universal prediction of cellular phenotypes;2024-08-12

3. Design, synthesis, antiproliferative, antituberculosis and in-silico analysis of New Schiff base derivatives of cyclohepta[b]thiophene;Journal of Molecular Structure;2024-08

4. Current State of Targeted Therapy in Adult Langerhans Cell Histiocytosis and Erdheim–Chester Disease;Targeted Oncology;2024-07-11

5. Viral microRNA regulation of Akt is necessary for reactivation of Human Cytomegalovirus from latency in CD34⁺hematopoietic progenitor cells and humanized mice;2024-05-24