A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

Author:

Karageorgis AnastassiaORCID,Lenhard Stephen C.,Yerby Brittany,Forsgren Mikael F.,Liachenko Serguei,Johansson Edvin,Pilling Mark A.,Peterson Richard A.,Yang Xi,Williams Dominic P.,Ungersma Sharon E.,Morgan Ryan E.,Brouwer Kim L. R.,Jucker Beat M.,Hockings Paul D.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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3. Drug safety sciences and the bottleneck in drug development;PB Watkins;Clinical pharmacology and therapeutics,2011

4. Alanine aminotransferase: a clinical and regulatory tool for detecting liver injury-past, present, and future;JR Senior;Clinical pharmacology and therapeutics,2012

5. Development of blood biomarkers for drug-induced liver injury: an evaluation of their potential for risk assessment and diagnostics;DE Amacher;Molecular diagnosis & therapy,2013

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