1. Novum Organum: True Directions Concerning the Interpretation of Nature (with other parts of The Great Instauration);F Bacon,1620
2. The Design of Experiments;RA Fisher,1971
3. The logic of scientific discovery;K Popper,1934
4. Conjectures and Refutations;K Popper,1968
5. How to increase value and reduce waste when research priorities are set;I Chalmers;Lancet,2014