Abstract
Noise-induced-hearing-loss(NIHL) is a common occupational disease caused by various environmental and biological factors. To investigate the association between TAB2 and the susceptibility of NIHL of people exposed to occupational environments, a genetic association study was performed on selected companies with 588 cases and 537 healthy control subjects. Five selected single nucleotide polymorphisms (SNPs) in TAB2,incoluding rs2744434, rs521845, rs652921, rs7896, rs9485372, were genotyped after a collection of DNA samples. Evident differences in participants between the case group and the control group reveals the result that people with the TAB2 has a high probability of getting NIHL. The results show that rs521845 is deeply associated with the risk of NIHL and is available for the diagnosis in the future.
Funder
Six Talent Peaks Project in Jiangsu Province
Jiangsu Province’s Outstanding Medical Academic 5 Leader program
Preventive Medicine Foundation of Jiangsu
Publisher
Public Library of Science (PLoS)
Reference38 articles.
1. Otoprotective Effects of Stephania tetrandra S. Moore Herb Isolate against Acoustic Trauma;Y Yu;J Assoc Res Otolaryngol,2018
2. Analysis on Risk Factors of Depressive Symptoms in Occupational Noise-induced Hearing Loss Patients: A Cross-sectional Study;XF Deng;Noise & health,2019
3. Prevalence of noise induced hearing loss among Jordanian industrial workers and its associated factors;M Almaayeh;Work-a Journal of Prevention Assessment & Rehabilitation,2018
4. Noise and Occupational Medicine Common Practice Problems;A Phillips;Journal Of Occupational And Environmental Medicine,2019
5. Association between Smoking and Noise-Induced Hearing Loss: A Meta-Analysis of Observational Studies;XW Li;International Journal of Environmental Research and Public Health,2020
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