Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative Gene-Reference-Cited by-同舟云学术

Meta-analysis Reveals Genome-Wide Significance at 15q13 for Nonsyndromic Clefting of Both the Lip and the Palate, and Functional Analyses Implicate GREM1 As a Plausible Causative Gene

Published:2016-03-11 Issue:3 Volume:12 Page:e1005914
ISSN:1553-7404
Container-title:PLOS Genetics
language:en
Short-container-title:PLoS Genet

Author:

Ludwig Kerstin U.,Ahmed Syeda Tasnim,Böhmer Anne C.,Sangani Nasim Bahram,Varghese Sheryil,Klamt Johanna,Schuenke Hannah,Gültepe Pinar,Hofmann Andrea,Rubini Michele,Aldhorae Khalid Ahmed,Steegers-Theunissen Regine P.,Rojas-Martinez Augusto,Reiter Rudolf,Borck Guntram,Knapp Michael,Nakatomi Mitsushiro,Graf Daniel,Mangold Elisabeth,Peters Heiko

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference63 articles.

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3. Meta-analysis of 13 genome scans reveals multiple cleft lip/palate genes with novel loci on 9q21 and 2q32-35;ML Marazita;Am J Hum Genet,2004

4. FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate;LM Moreno;Hum Mol Genet,2009

5. Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip;F Rahimov;Nat Genet,2008

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