Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

Author:

Fehrmann Rudolf S. N.,Jansen Ritsert C.,Veldink Jan H.,Westra Harm-Jan,Arends Danny,Bonder Marc Jan,Fu Jingyuan,Deelen Patrick,Groen Harry J. M.,Smolonska Asia,Weersma Rinse K.,Hofstra Robert M. W.,Buurman Wim A.,Rensen Sander,Wolfs Marcel G. M.,Platteel Mathieu,Zhernakova Alexandra,Elbers Clara C.,Festen Eleanora M.,Trynka Gosia,Hofker Marten H.,Saris Christiaan G. J.,Ophoff Roel A.,van den Berg Leonard H.,van Heel David A.,Wijmenga Cisca,te Meerman Gerard J.,Franke Lude

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics(clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference54 articles.

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4. REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.;PK Gregersen;Nat Genet,2009

5. Common variants at five new loci associated with early-onset inflammatory bowel disease.;M Imielinski;Nat Genet,2009

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