Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development-Reference-Cited by-同舟云学术

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development

Published:2016-08-05 Issue:8 Volume:12 Page:e1006242
ISSN:1553-7404
Container-title:PLOS Genetics
language:en
Short-container-title:PLoS Genet

Author:

Giannikou Krinio,Malinowska Izabela A.,Pugh Trevor J.,Yan Rachel^ORCID,Tseng Yuen-Yi,Oh Coyin,Kim Jaegil,Tyburczy Magdalena E.,Chekaluk Yvonne,Liu Yang,Alesi Nicola,Finlay Geraldine A.,Wu Chin-Lee,Signoretti Sabina,Meyerson Matthew,Getz Gad,Boehm Jesse S.^ORCID,Henske Elizabeth P.^ORCID,Kwiatkowski David J.

Funder

Broad Institute Scientific Projects to Accelerate Research and Collaboration (SPARC)

National Heart, Lung, and Blood Institute

National Cancer Institute

Engles Fund

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics(clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference62 articles.

1. Loss of heterozygosity in the tuberous sclerosis (TSC2) region of chromosome band 16p13 occurs in sporadic as well as TSC-associated renal angiomyolipomas;EP Henske;Genes, Chromosomes & Cancer,1995

2. Renal angiomyolipomas from patients with sporadic lymphangiomyomatosis contain both neoplastic and non-neoplastic vascular structures;M Karbowniczek;Am J Pathol,2003