Cell Specific eQTL Analysis without Sorting Cells

Author:

Westra Harm-Jan,Arends Danny,Esko Tõnu,Peters Marjolein J.,Schurmann Claudia,Schramm Katharina,Kettunen Johannes,Yaghootkar Hanieh,Fairfax Benjamin P.,Andiappan Anand Kumar,Li Yang,Fu Jingyuan,Karjalainen Juha,Platteel Mathieu,Visschedijk Marijn,Weersma Rinse K.,Kasela Silva,Milani Lili,Tserel Liina,Peterson Pärt,Reinmaa Eva,Hofman Albert,Uitterlinden André G.,Rivadeneira Fernando,Homuth Georg,Petersmann Astrid,Lorbeer Roberto,Prokisch Holger,Meitinger Thomas,Herder Christian,Roden Michael,Grallert Harald,Ripatti Samuli,Perola Markus,Wood Andrew R.,Melzer David,Ferrucci Luigi,Singleton Andrew B.,Hernandez Dena G.,Knight Julian C.,Melchiotti Rossella,Lee Bernett,Poidinger Michael,Zolezzi Francesca,Larbi Anis,Wang De Yun,van den Berg Leonard H.,Veldink Jan H.,Rotzschke Olaf,Makino Seiko,Salomaa Veikko,Strauch Konstantin,Völker Uwe,van Meurs Joyce B. J.,Metspalu Andres,Wijmenga Cisca,Jansen Ritsert C.,Franke Lude

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference35 articles.

1. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits;LA Hindorff;Proc Natl Acad Sci U S A,2009

2. Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA;RSN Fehrmann;PLoS Genet,2011

3. Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs;CD Brown;PLoS Genet,2013

4. Genetics of gene expression in primary immune cells identifies cell-specific master regulators and roles of HLA alleles;BPB Fairfax;Nat Genet,2012

5. Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression;J Fu;PLoS Genet,2012

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