Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

Author:

Day FelixORCID,Karaderi Tugce,Jones Michelle R.,Meun CindyORCID,He Chunyan,Drong Alex,Kraft Peter,Lin Nan,Huang Hongyan,Broer Linda,Magi Reedik,Saxena Richa,Laisk TriinORCID,Urbanek Margrit,Hayes M. Geoffrey,Thorleifsson Gudmar,Fernandez-Tajes Juan,Mahajan AnubhaORCID,Mullin Benjamin H.,Stuckey Bronwyn G. A.,Spector Timothy D.,Wilson Scott G.,Goodarzi Mark O.,Davis Lea,Obermayer-Pietsch Barbara,Uitterlinden André G.,Anttila VerneriORCID,Neale Benjamin M.ORCID,Jarvelin Marjo-RiittaORCID,Fauser Bart,Kowalska Irina,Visser Jenny A.ORCID,Andersen Marianne,Ong KenORCID,Stener-Victorin ElisabetORCID,Ehrmann David,Legro Richard S.,Salumets AndresORCID,McCarthy Mark I.,Morin-Papunen Laure,Thorsteinsdottir UnnurORCID,Stefansson Kari,Styrkarsdottir UnnurORCID,Perry John R. B.,Dunaif AndreaORCID,Laven Joop,Franks Steve,Lindgren Cecilia M.,Welt Corrine K.ORCID,

Funder

Medical Research Council

National Cancer Institute

European Regional Development Fund

European Union Horizon 2020

National Institute of Child Health and Human Development

American Diabetes Association

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics(clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference71 articles.

1. Heritability of polycystic ovary syndrome in a Dutch twin-family study;J.M. Vink;J Clin Endocrinol Metab,2006

2. Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS;M.D. Kahsar-Miller;Fertil Steril,2001

3. Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome;R.S. Legro;Proc Natl Acad Sci U S A,1998

4. A twin study of polycystic ovary syndrome and lipids;S. Jahanfar;Gynecol Endocrinol,1997

5. A twin study of polycystic ovary syndrome;S. Jahanfar;Fertil Steril,1995

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