Native Pyroglutamation of Huwentoxin-IV: A Post-Translational Modification that Increases the Trapping Ability to the Sodium Channel
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference36 articles.
1. Use of venom peptides to probe ion channel structure and function;S Dutertre;J Biol Chem,2010
2. Proteomic and peptidomic characterization of the venom from the Chinese bird spider, Ornithoctonus huwena Wang;C Yuan;J Proteome Res,2007
3. An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [ = Ornithoctonus huwena (Wang)];S Liang;Toxicon,2004
4. Function and solution structure of Huwentoxin-X, a specific blocker of N-type calcium channels, from the Chinese bird spider Ornithoctonus huwena;Z Liu;J Biol Chem,2006
5. The effect of Huwentoxin-I on Ca(2+) channels in differentiated NG108-15 cells, a patch-clamp study;K Peng;Toxicon,2001
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Structure-function and rational design of a spider toxin Ssp1a at human voltage-gated sodium channel subtypes;Frontiers in Pharmacology;2023-11-13
2. Engineering of a Spider Peptide via Conserved Structure-Function Traits Optimizes Sodium Channel Inhibition In Vitro and Anti-Nociception In Vivo;Frontiers in Molecular Biosciences;2021-09-21
3. A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists;Journal of Medicinal Chemistry;2020-06-30
4. Structure–Function and Therapeutic Potential of Spider Venom-Derived Cysteine Knot Peptides Targeting Sodium Channels;Frontiers in Pharmacology;2019-04-11
5. The Venom of Ornithoctonus huwena affect the electrophysiological stability of neonatal rat ventricular myocytes by inhibiting sodium, potassium and calcium current;Channels;2018-01-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3