Re-Directing an Alkylating Agent to Mitochondria Alters Drug Target and Cell Death Mechanism

Author:

Mourtada Rida,Fonseca Sonali B.,Wisnovsky Simon P.,Pereira Mark P.,Wang Xiaoming,Hurren Rose,Parfitt Jeremy,Larsen Lesley,Smith Robin A. J.,Murphy Michael P.,Schimmer Aaron D.,Kelley Shana O.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference34 articles.

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3. The intravenous, subcutaneous and cutaneous toxicity of bis (beta-chloroethyl) sulfide (mustard gas) and of various derivatives;WP Anslow Jr;J Pharmacol Exp Ther,1948

4. Chemical approaches to the discovery and development of cancer therapies;S Neidle;Nat Rev Cancer,2005

5. The reaction of mono- and di-functional alkylating agents with nucleic acids;P Brookes;Biochem J,1961

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