Protein-Protein Interactions as a Strategy towards Protein-Specific Drug Design: The Example of Ataxin-1
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Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference48 articles.
1. Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1;HT Orr;Nat Genet,1993
2. Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1;HY Zoghbi;J Biol Chem,2009
3. The pathogenesis of spinocerebellar ataxia;AH Koeppen;Cerebellum,2005
4. Polyglutamine and neurodegeneration: structural aspects;L Masino;Protein Pept Lett,2004
5. Polyglutamine is not all: the functional role of the AXH domain in the ataxin-1 protein;C de Chiara;J Mol Biol,2005
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3. A Structural Study of the Cytoplasmic Chaperone Effect of 14-3-3 Proteins on Ataxin-1;Journal of Molecular Biology;2021-09
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