Effects of Highly Conserved Major Histocompatibility Complex (MHC) Extended Haplotypes on Iron and Low CD8+ T Lymphocyte Phenotypes in HFE C282Y Homozygous Hemochromatosis Patients from Three Geographically Distant Areas

Author:

Costa Mónica,Cruz Eugénia,Barton James C.,Thorstensen Ketil,Morais Sandra,da Silva Berta M.,Pinto Jorge P.,Vieira Cristina P.,Vieira Jorge,Acton Ronald T.,Porto Graça

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference45 articles.

1. The human Major Histocompatibility Complex as a paradigm in genomics research;C Vandiedonck;Brief Funct Genomic Proteomic,2009

2. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis;JN Feder;Nat Genet,1996

3. Porto G, Sousa MD (2000) Variation of hemochromatosis prevalence and genotype in national groups. In: Barton J E, CQ, editor, editor. Hemochromatosis Genetics, Pathophysiology, Diagnosis, and Treatment: Cambridge University Press. pp. 51–62.

4. A study of 609 HLA haplotypes marking for the hemochromatosis gene: (1) mapping of the gene near the HLA-A locus and characters required to define a heterozygous population and (2) hypothesis concerning the underlying cause of hemochromatosis-HLA association;M Simon;Am J Hum Genet,1987

5. Recombinations defining centromeric and telomeric borders for the hereditary haemochromatosis locus;RS Ajioka;J Med Genet,1997

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