Gadd153 and NF-κB Crosstalk Regulates 27-Hydroxycholesterol-Induced Increase in BACE1 and β-Amyloid Production in Human Neuroblastoma SH-SY5Y Cells

Author:

Marwarha Gurdeep,Raza Shaneabbas,Prasanthi Jaya R. P.,Ghribi Othman

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference58 articles.

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2. beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms;C Haass;J Biol Chem,1993

3. Beta-secretase cleavage of Alzheimer’s amyloid precursor protein by the transmembrane aspartic protease BACE;R Vassar;Science,1999

4. Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease;H Fukumoto;Arch Neurol,2002

5. alpha- and beta-secretase: profound changes in Alzheimer’s disease;SJ Tyler;Biochem Biophys Res Commun,2002

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