Enteric infection coupled with chronic Notch pathway inhibition alters colonic mucus composition leading to dysbiosis, barrier disruption and colitis

Author:

Ahmed Ishfaq,Roy Badal C.,Raach Rita-Marie T.,Owens Sarah M.,Xia Lijun,Anant Shrikant,Sampath Venkatesh,Umar ShahidORCID

Funder

National Institutes of Health

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference72 articles.

1. A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion;GM Birchenough;Science,2016

2. Mucin dynamics and enteric pathogens;MA McGuckin;Nature reviews Microbiology,2011

3. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria;ME Johansson;Proc Natl Acad Sci U S A,2008

4. Role of mucus layers in gut infection and inflammation;GC Hansson;Curr Opin Microbiol,2011

5. Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans;G An;J Exp Med,2007

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