A Novel Simple Method for Determining CYP2D6 Gene Copy Number and Identifying Allele(s) with Duplication/Multiplication

Author:

Langaee Taimour,Hamadeh Issam,Chapman Arlene B.,Gums John G.,Johnson Julie A.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference20 articles.

1. Pharmacogenomics and individualized drug therapy;M Eichelbaum;Annu Rev Med,2006

2. The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene;S Kimura;Am J Hum Genet,1989

3. Pharmacogenetic screening of the gene deletion and duplications of CYP2D6;I Meijerman;Drug Metab Rev,2007

4. Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype;KR Crews;Clin Pharmacol Ther,2012

5. The CYP2D6 activity score: Translating genotype information into a qualitative measure of phenotype;A Gaedigk;Clin Pharmacol Ther,2008

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