Target Modulation by a Kinase Inhibitor Engineered to Induce a Tandem Blockade of the Epidermal Growth Factor Receptor (EGFR) and c-Src: The Concept of Type III Combi-Targeting-Reference-Cited by-同舟云学术

Target Modulation by a Kinase Inhibitor Engineered to Induce a Tandem Blockade of the Epidermal Growth Factor Receptor (EGFR) and c-Src: The Concept of Type III Combi-Targeting

Published:2015-02-06 Issue:2 Volume:10 Page:e0117215
ISSN:1932-6203
Container-title:PLOS ONE
language:en
Short-container-title:PLoS ONE

Author:

Rao Suman,Larroque-Lombard Anne-Laure,Peyrard Lisa,Thauvin Cédric,Rachid Zakaria,Williams Christopher,Jean-Claude Bertrand J.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference48 articles.

1. Targeting the cancer kinome through polypharmacology;ZA Knight;Nat Rev Cancer,2010

2. Do molecularly targeted agents in oncology have reduced attrition rates?;I Walker;Nat Rev Drug Discov,2009

3. Polypharmacology: drug discovery for the future;AS Reddy;Expert Rev Clin Pharmacol,2014

4. Subcellular distribution of a fluorescence-labeled combi-molecule designed to block epidermal growth factor receptor tyrosine kinase and damage DNA with a green fluorescent species;MI Todorova;Mol Cancer Ther,2010

5. The combi-targeting concept: mechanism of action of the pleiotropic combi-molecule RB24 and discovery of a novel cell signaling-based combination principle;R Banerjee;Cell Signal,2011

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Endothelial Cell-Derived Soluble CD200 Determines the Ability of Immune Cells to Cross the Blood–Brain Barrier;International Journal of Molecular Sciences;2024-08-27

2. Molecular Analysis of the Superior Efficacy of a Dual Epidermal Growth Factor Receptor (EGFR)-DNA-Targeting Combi-Molecule in Comparison with Its Putative Prodrugs 6-Mono-Alkylamino- and 6,6-Dialkylaminoquinazoline in a Human Osteosarcoma Xenograft Model;Cells;2023-03-16

3. Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy;Journal of Medicinal Chemistry;2022-03-21

4. β-Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation;Biomolecules;2021-11-22

5. How to determine the statistical significance of trends in seasonal records: application to Antarctic temperatures;Climate Dynamics;2021-10-05