A Fatal Combination: A Thymidylate Synthase Inhibitor with DNA Damaging Activity

Author:

Ligasová Anna,Strunin Dmytro,Friedecký David,Adam Tomáš,Koberna Karel

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference36 articles.

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3. 5-alkynyl analogs of arabinouridine and 2′-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells;WA Cristofoli;J Med Chem,2007

4. 5-Alkynyl-2′-deoxyuridines: chromatography-free synthesis and cytotoxicity evaluation against human breast cancer cells;S Meneni;Bioorg Med Chem,2007

5. 5-Nitro-2′-deoxyuridine and 5-nitro-2′-deoxyuridine 5′-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo;E De Clercq;Mol Pharmacol,1978

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