The Inhibition of N-Glycosylation of Glycoprotein 130 Molecule Abolishes STAT3 Activation by IL-6 Family Cytokines in Cultured Cardiac Myocytes

Author:

Matsuo Reo,Morihara Hirofumi,Mohri Tomomi,Murasawa Shiho,Takewaki Kana,Nakayama Hiroyuki,Maeda Makiko,Fujio Yasushi

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference19 articles.

1. Glycoprotein 130 cytokine signal as a therapeutic target against cardiovascular diseases. J Pharmacol Sci;Y Fujio,2011

2. Cardiortrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series via gp130/leukemia inhibitory factor receptor-dependent pathways. J Biol Chem;KC Wollert,1996

3. Identification of cardiac myocytes as targets of interleukin-11, a cardioprotective cytokine. Cytokine;R Kimura,2007

4. Interleukin-6 family of cytokines and gp130. Blood;T Kishimoto,1995

5. Determination of the disulfide structure and N-glycosylation sites of the extracellular domain of the human signal transducer gp130. J Biol Chem;RL Moritz,2001

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