Inhibitor and Substrate Binding Induced Stability of HIV-1 Protease against Sequential Dissociation and Unfolding Revealed by High Pressure Spectroscopy and Kinetics

Author:

Ingr Marek,Lange Reinhard,Halabalová Věra,Yehya Alaa,Hrnčiřík Josef,Chevalier-Lucia Dominique,Palmade Laetitia,Blayo Claire,Konvalinka Jan,Dumay Eliane

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference41 articles.

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2. Structural biology of HIV;BG Turner;J Mol Biol,1999

3. Current and Novel Inhibitors of HIV Protease;J Pokorná;Viruses,2009

4. Activity and dimerization of human immunodeficiency virus protease as a function of solvent composition and enzyme concentration;SP Jordan;J Biol Chem,1992

5. Determination of kinetic rate constants for the binding of inhibitors to HIV-1 protease and for the association and dissociation of active homodimer;CA Pargellis;Biochemistry,1994

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