Abstract
The real-time analysis of infectious disease surveillance data is essential in obtaining situational awareness about the current dynamics of a major public health event such as the COVID-19 pandemic. This analysis of e.g., time-series of reported cases or fatalities is complicated by reporting delays that lead to under-reporting of the complete number of events for the most recent time points. This can lead to misconceptions by the interpreter, for instance the media or the public, as was the case with the time-series of reported fatalities during the COVID-19 pandemic in Sweden. Nowcasting methods provide real-time estimates of the complete number of events using the incomplete time-series of currently reported events and information about the reporting delays from the past. In this paper we propose a novel Bayesian nowcasting approach applied to COVID-19-related fatalities in Sweden. We incorporate additional information in the form of time-series of number of reported cases and ICU admissions as leading signals. We demonstrate with a retrospective evaluation that the inclusion of ICU admissions as a leading signal improved the nowcasting performance of case fatalities for COVID-19 in Sweden compared to existing methods.
Funder
NordForsk
Swedish National Infrastructure for Computing
Publisher
Public Library of Science (PLoS)
Subject
Computational Theory and Mathematics,Cellular and Molecular Neuroscience,Genetics,Molecular Biology,Ecology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics
Reference25 articles.
1. Mathematical models to guide pandemic response: Models can be used to learn from the past and prepare for the future;C Metcalf;Science,2020
2. Nowcasting epidemics of novel pathogens: lessons from COVID-19;JT Wu;Nat Med,2021
3. Folkhälsomyndigheten. The Public Health Agency of Sweden’s COVID-19 data portal; Accessed 2022-03-07. https://www.folkhalsomyndigheten.se/smittskydd-beredskap/utbrott/aktuella-utbrott/covid-19/statistik-och-analyser/.
4. Nowcasting pandemic influenza A/H1N1 2009 hospitalizations in the Netherlands;T Donker;Eur J Epidemiol,2011
5. Bayesian nowcasting during the STEC 0104:H4 outbreak in Germany, 2011;M Höhle;Biometrics,2014
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