The onchocerciasis hypothesis of nodding syndrome-Reference-Cited by-同舟云学术

The onchocerciasis hypothesis of nodding syndrome

Published:2023-08-17 Issue:8 Volume:17 Page:e0011523
ISSN:1935-2735
Container-title:PLOS Neglected Tropical Diseases
language:en
Short-container-title:PLoS Negl Trop Dis

Author:

Colebunders Robert^ORCID,Hadermann Amber,Siewe Fodjo Joseph Nelson

Abstract

Nodding syndrome (NS) is a phenotypic presentation of onchocerciasis-associated epilepsy (OAE). OAE is an important public health problem in areas with high ongoing Onchocerca volvulus transmission. OAE, including NS, is preventable by strengthening onchocerciasis elimination programs. The presence of tau in OAE postmortem brains could be the consequence of neuroinflammation directly or indirectly induced by O. volvulus. Omics research is needed to investigate whether O. volvulus worms contain a neurotropic virus.

Funder

Research Foundation - Flanders

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference18 articles.

1. Nodding syndrome in Kitgum District, Uganda: association with conflict and internal displacement;JL Landis;BMJ Open,2014

2. Onchocerciasis-associated epilepsy: an update and future perspectives;A Hadermann;Trends Parasitol,2023

3. Persons with onchocerciasis-associated epilepsy and nodding seizures have a more severe form of epilepsy with more cognitive impairment and higher levels of Onchocerca volvulus infection;G Abd-Elfarag;Epileptic Disord,2020

4. Prevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of onchocerciasis control measures;N Gumisiriza;Infect Dis Poverty,2020

5. High prevalence of onchocerciasis-associated epilepsy in villages in Maridi County, Republic of South Sudan: A community-based survey;R Colebunders;Seizure,2018

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2. Methodological challenges for conducting case-control studies to investigate the association between onchocerciasis and epilepsy including nodding syndrome;Brain Communications;2023-12-20

3. Onchocerciasis-associated epilepsy: an explorative case-control study with viral metagenomic analyses on Onchocerca volvulus;F1000Research;2023-12-11

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5. Nodding syndrome, populations at risk need to be aware this is a preventable condition;Brain Communications;2023