The Active Tamoxifen Metabolite Endoxifen (4OHNDtam) Strongly Down-Regulates Cytokeratin 6 (CK6) in MCF-7 Breast Cancer Cells

Author:

Helland Thomas,Gjerde Jennifer,Dankel Simon,Fenne Ingvild S.,Skartveit Linn,Drangevåg Andreas,Bozickovic Olivera,Flågeng Marianne Hauglid,Søiland Håvard,Mellgren Gunnar,Lien Ernst A.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference53 articles.

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3. Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxytamoxifen isomers in MCF-7 human breast cancer cells;BS Katzenellenbogen;Cancer Res,1984

4. Breast cancer chemoprevention phase I evaluation of biomarker modulation by arzoxifene, a third generation selective estrogen receptor modulator;CJ Fabian;Clin Cancer Res,2004

5. Hydroxylated metabolites of tamoxifen are formed in vivo and bound to estrogen receptor in target tissues;J-L Borgna;J Biol Chem,1981

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