Dynamic Modulation of Thymidylate Synthase Gene Expression and Fluorouracil Sensitivity in Human Colorectal Cancer Cells

Author:

Wakasa Kentaro,Kawabata Rumi,Nakao Seiki,Hattori Hiroyoshi,Taguchi Kenichi,Uchida Junji,Yamanaka Takeharu,Maehara Yoshihiko,Fukushima Masakazu,Oda Shinya

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference23 articles.

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2. Mechanisms of cross-resistance to methotrexate and 5-fluorouracil in an A2780 human ovarian carcinoma cell subline resistant to cisplatin;EM Newman;Biochem Pharmacol,1988

3. Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death;A Yoshioka;J Biol Chem,1987

4. Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen;JL Grem;Clin Cancer Res,2001

5. Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil;M Ciaparrone;Oncology,2006

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