PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage

Author:

Stiles Megan,Moiseyev Gennadiy P.,Budda Madeline L.,Linens Annette,Brush Richard S.,Qi Hui,White Gary L.,Wolf Roman F.,Ma Jian-xing,Floyd Robert,Anderson Robert E.,Mandal Nawajes A.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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4. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane;J Liu;J Biol Chem,2000

5. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells;JR Sparrow;Invest Ophthalmol Vis Sci,2000

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