Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking

Author:

Wei Yu,Li Jinlong,Qing Jie,Huang Mingjie,Wu Ming,Gao Fenghua,Li Dongmei,Hong Zhangyong,Kong Lingbao,Huang Weiqiang,Lin Jianping

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference98 articles.

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2. WHO. Hepatitis C. Fact sheet no.164, 2014. Available: http://www.who.int/mediacentre/factsheets/fs164/en/. Accessed 10 September 2014.

3. HEP: Available: http://www.hepmag.com/drug_list_hepatitisc.shtml. Accessed 17 September 2014.

4. Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection;C Sarrazin;Gastroenterology,2010

5. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus;SE Behrens;EMBO J,1996

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